Episode 34: Why NASH Drug Trials Fail: A Thoughtful, Challenging Theory

NASH Drug Trials
Prof. Dr. Jörn M. Schattenberg joins the Surfers to discuss his recent article in Expert Opinion on Investigational Drugs dissecting recent drug trial failures.

Prof. Dr. Jörn M. Schattenberg g joins Stephen, Donna, Louise and Roger to discuss his recent article “The Nonalcoholic Steatohepatitis (NASH) drug development graveyard: established hurdles and planning for future successes.” The discussion started with lessons from failed trials, focusing on the importance of utilizing Phase 2 trials to test hypotheses and establish appropriate targets. From there, Surfers went on to discuss commercial and patient-focused definitions of what makes a clinical trial successful.

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