Category: Histopathology

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S3-E40.2 - A Simple Diagnostic Algorithm for Lean NASH

S3-E40.2 – A Simple Diagnostic Algorithm for Lean NASH

Co-authors Michelle Long and Mazen Noureddin join Louise Campbell and Roger Green to discuss their recent publication on Best Practice in lean NASH. This conversation focuses on the elegant one-page diagnostic algorithm they recommend for diagnosing Lean NASH in “normal” BMI patients with signs of liver disease.

S3-E38.5 - From the Vault: NAIL-NIT tackles NAS Score Challenges

S3-E38.5 – From the Vault: NAIL-NIT tackles NAS Score Challenges

From February of this year, Stephen Harrison and Mazen Noureddin join Jörn Schattenberg, Louise Campbell and Roger Green to discuss the formation of the new NAIL-NIT consortium, led by Stephen and Mazen. This conversation focuses on the specific challenges inherent in the NAS scores.

S3-E38.3 - From the Vault: Learning Fibrosis at Paris NASH

S3-E38.3 – From the Vault: Learning Fibrosis at Paris NASH

From September 2021, Stephen Harrison and Jörn Schattenberg lead the Surfers on a deep dive into the fibrosis section of the recent Paris NASH conference. The conversation focuses on fibrosis and the role of stellate cells in fibrogenesis.

S3-E36.5 - REGENERATE Redux: Clearing The Finish Line?

S3-E36.5 – REGENERATE Redux: Clearing The Finish Line?

Stephen Harrison leads the rest of the Surfers (Jörn Schattenberg, Louise Campbell and Roger Green), through a discussion of Intercept Pharmaceuticals’ July 7 press release on re-analysis of the REGENERATE trial evaluating obeticholic acid (OCA) for treating of NASH fibrosis. This conversation asks (and attempts to answer) whether the REGENERATE reanalysis is likely to succeed in getting the drug approved.

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