Day: October 30, 2021

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Can MRE Provide Reliable, Non-Invasive Clinical Trial Endpoints?

S2-E52.3 – Can MRE Provide Reliable, Non-Invasive Clinical Trial Endpoints?

Alina Allen and Stephen Harrison spearhead a discussion on how MRE results can provide a foundation for developing Subpart H Clinical Trial Endpoints from non-invasive testing data. Their comments stem from Alina’s presentation of the recent Mayo Clinic paper, “MRE for Prediction of Long-Term Progression and Outcome in Chronic Liver Disease: A Retrospective Study.” In this conversation, Alina summarizes the paper, after which Stephen Harrison asks questions about availability of subgroup analysis.

S2-E52.2 - How Liver Stiffness Measures Can Improve Practical Patient Management

S2-E52.2 – How Liver Stiffness Measurements Can Improve Practical Patient Management

Alina Allen and Ian Rowe discuss how Liver Stiffness Measurements (LSM) can improve individual patient treatment in pre-cirrhotic and compensated cirrhotic patients. Their comments stem from Alina’s presentation of the recent Mayo Clinic paper, “MRE for Prediction of Long-Term Progression and Outcome in Chronic Liver Disease: A Retrospective Study.” In this conversation, Alina summarizes the paper, after which Stephen Harrison asks questions about the availability of subgroup analysis.